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Prof. Bilezikiandi of New York explained this important, innovative technique.

The central problem linked to replacement therapy is adequate management of

calcium and Vitamin D dosage, and this is not always an easy goal to attain.

How much Vitamin D need we administer to these patient for adequate control

of calcemia and what is the

price they pay? How can we

counteract the negative effects

of this replacement therapy on

bone metabolism? How can we

maintain quality of life at ac-

ceptable levels? According to

Prof. Bilezikian, the real problem is that patients af-

fected with hypoparathyroidism often receive exces-

sively high or insufficient doses of calcium and Vita-

min D and, in both cases, the outcome for their

health can be serious. Hypoparathyroidism is the only specific hormonal deficit disorder not currently

treatable via a well-defined hormone replacement therapy. Or at least this was true until today, since

in January 2015 the FDA approved marketing of a new releasing hormone denominated rhPTH (1-84)

for use in treatment of patients with hypoparathyroidism.

Fondazione

Internazionale

Menarini

To find answers to these and other interesting queries and for more in-depth in-

formation, go to

www.fondazione-menarini.it/... R

egister at the site to access the

multimedia material.

John P. Bilezikian

New York - USA

Replacement therapy with PTH peptides

What data have been published on this new treatment adjunct? - - - What is its ef-

fect on bone metabolism? - - - What is its effect on calcemia? - - - And on quality

of life?